Guinea Bissau’s Prime Minister Nuno Gomes Nabiam has tested positive for coronavirus, the health ministry has said.
Interior Minister Botche Cande and two other ministers also have Covid-19.
Mr Nabiam said that several members of an inter-ministerial coronavirus committee had the disease.
Guinea Bissau has a poor healthcare system due to mismanagement and a lack of resources.
The country has so far confirmed 205 coronavirus cases and one death.
