Chelsea midfielder N’Golo Kante has tested positive for Covid-19 and has gone into self-isolation.
Manager Thomas Tuchel confirmed Kante must “quarantine and follow the government protocols.”
Tuchel said Kante was not at training on Tuesday as Chelsea prepared for their Champions League Group H match against Juventus on Wednesday.
The 30-year-old will also miss Saturday’s Premier League clash with Southampton and his participation in France’s Nations League clash with Belgium on October 7 could also be in doubt.
Tuchel said Christian Pulisic, Mason Mount and Reece James will also be unavailable against Juventus.
Pulisic and Mount have been out with prior injuries, while James twisted his ankle and was withdrawn on 29 minutes of the 1-0 home defeat to Manchester City on Saturday.
Juventus duo Paulo Dybala and Alvaro Morata have been ruled out of the Champions League group-stage clash with Chelsea this week because of injuries.
Dybala suffered a thigh problem in Sunday’s Serie A win over Sampdoria – withdrawn in tears after just 22 minutes and having scored his side’s opener, while Morata also came off with eight minutes of normal time remaining.
Manager Massimiliano Allegri confirmed both players will miss the tie at Juventus Stadium and the subsequent derby with Torino, but he hopes to have them back after the next international break in early October.