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Genetics and environment key factors in Parkinson’s disease – Neurologist

Genetics and environment key factors in Parkinson’s disease – Neurologist
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By Sarah Baafi

While Parkinson’s disease is often associated with ageing and tremors, experts say the condition is influenced by both genetic and environmental factors.

Speaking on GTV Breakfast show, neurologist and senior physician at Komfo Anokye Teaching Hospital (KATH), Dr Vida Obese, who is also Founder and President of the Anidaso Parkinson’s Disease Foundation, highlighted the importance of understanding these factors to better manage and prevent the disease.

“Environmental factors play a significant role,” Dr Obese explained. “Long-term exposure to pesticides, heavy metals such as mercury and manganese, and industrial pollutants can increase the risk of developing Parkinson’s disease. It is the interplay between genetics and the environment that often triggers the condition.”

She noted that genetics account for only a portion of cases.

“About 26% of Parkinson’s cases are linked to genetic mutations, but no single gene causes the disease. Multiple genes may increase susceptibility, and what is found in other populations may not apply to Africans. This is why local research is crucial,” she said.

Dr Obese emphasised that managing Parkinson’s goes beyond medication.

“Exercise plays a key role in protecting brain health and improving dopamine release. Even walking three times a week helps. Activities like cycling, dancing, or other exercises that engage both body and mind are highly beneficial,” she said.

To mark World Parkinson’s Day on April 11, Dr Obese announced an awareness and fundraising initiative.

“We are using cycling to raise awareness and support patients. Cycling engages the whole body and cognitive abilities, making it an excellent way to promote health while highlighting the disease,” she said.

She concluded by stressing the need for advocacy and support.

“Many patients, especially those with limited resources, struggle to manage Parkinson’s. This pushes us to do more research, support patients, and raise awareness. It’s not just about medication; it’s about a holistic approach to care.”

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